Until now, Cloud solutions have been primarily focused on running important business applications like CRM, ERP, email and other database applications. Cyclone™ capitalizes on twenty years of SGI HPC expertise to specifically address the emerging technical applications market to service science and engineering needs, which rely on very high-end computational hardware, software and networking. Cyclone currently supports six domains and many applications partners. Those leading domains include Computational Biology, Computational Chemistry and Materials, Computational Fluid Dynamics, Finite Element Analysis, Computational Electromagnetics and Ontologies. The following are Cyclone supported applications.